Article
Strong associations between RFLP and protein polymorphisms for CD46.
Immunogenetics - 1 Jan 1992
Wilton A N, Johnstone R W, McKenzie I F, Purcell D F
Abstract excerpt
Human CD46 (membrane cofactor protein) is a cell surface glycoprotein with cofactor activity for the factor I mediated cleavage of components C3b and C4b. Using a CD46 cDNA clone, three restriction enzymes give simple two allele restriction fragment length polymorphisms (RFLPs) in samples of over 300 Caucasians. For Pvu II, P1 with a 16.5 kilobase (kb) fragment and P2 with 14.8 kb + 1.9 kb fragments have...
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