Strong associations between RFLP and protein polymorphisms for CD46.

doi:10.1007/BF00215283

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Article

Strong associations between RFLP and protein polymorphisms for CD46.

Immunogenetics - 1 Jan 1992

Wilton A N, Johnstone R W, McKenzie I F, Purcell D F

Abstract excerpt

Human CD46 (membrane cofactor protein) is a cell surface glycoprotein with cofactor activity for the factor I mediated cleavage of components C3b and C4b. Using a CD46 cDNA clone, three restriction enzymes give simple two allele restriction fragment length polymorphisms (RFLPs) in samples of over...

Topics

Antigens, CD
DNA Probes
Genotype
Haplotypes
Humans
Membrane Cofactor Protein
Membrane Glycoproteins
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length

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