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Article

Polymorphic expression of CD46 protein isoforms due to tissue-specific RNA splicing.

Molecular immunology - 1 Oct 1993

Johnstone R W, Russell S M, Loveland B E, McKenzie I F

Abstract excerpt

CD46 is a member of the regulators of complement activation (RCA) family and serves to protect autologous cells from complement mediated lysis. The CD46 gene consists of 14 exons and extensive RNA splicing produces protein isoforms of different molecular weight. Predominant protein isoforms of 66 and 56 kDa arise from splicing in or out of exon 8 which encodes a region rich in serine, threonine and proline...

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Identifiers

PMID: 7692239
DOI: 10.1016/0161-5890(93)90038-d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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