Polymorphic expression of CD46 protein isoforms due to tissue-specific RNA splicing.

doi:10.1016/0161-5890(93)90038-d

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Article

Polymorphic expression of CD46 protein isoforms due to tissue-specific RNA splicing.

Molecular immunology - 1 Oct 1993

Johnstone R W, Russell S M, Loveland B E, McKenzie I F

Abstract excerpt

CD46 is a member of the regulators of complement activation (RCA) family and serves to protect autologous cells from complement mediated lysis. The CD46 gene consists of 14 exons and extensive RNA splicing produces protein isoforms of different molecular weight. Predominant protein isoforms of 66...

Topics

Alternative Splicing
Antigens, CD
Base Sequence
Blotting, Southern
Blotting, Western
Brain
Brain Chemistry
DNA
DNA Primers
Electrophoresis, Polyacrylamide Gel
Exons
Gene Expression
Humans
Kidney
Male
Membrane Cofactor Protein
Membrane Glycoproteins
Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7692239
DOI: 10.1016/0161-5890(93)90038-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7692239-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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