Article
T cells in hypersensitivity pneumonitis: effects of in vivo depletion of T cells in a mouse model.
American journal of respiratory cell and molecular biology - 1 Feb 1992
Denis M, Cormier Y, Laviolette M, Ghadirian E
Abstract excerpt
C57BL/6 mice were given intranasal instillation of optimal doses of the actinomycete Faeni rectivirgula 150 micrograms/mouse 3 days/wk), an important offending agent causing hypersensitivity pneumonitis. This instillation was associated with a very significant increase in the lung weight of the m...
Topics
- Actinomycetales Infections
- Alveolitis, Extrinsic Allergic
- Analysis of Variance
- Animals
- Bronchoalveolar Lavage Fluid
- Female
- Flow Cytometry
- Kinetics
- Lymphocyte Depletion
- Mice
- Mice, Inbred C57BL
- Micromonosporaceae
- Phenotype
- Pulmonary Fibrosis
- T-Lymphocyte Subsets
- T-Lymphocytes
- Tumor Necrosis Factor-alpha