Article
Lack of association between dopamine D1 and D2 receptor genes and bipolar affective disorder.
The American journal of psychiatry - 1 Feb 1992
Nöthen M M, Erdmann J, Körner J, Lanczik M, Fritze J, Fimmers R, Grandy D K, O'Dowd B, Propping P
Abstract excerpt
Fifty-six patients with bipolar affective disorder and 69 healthy control subjects were tested for association of restriction fragment length polymorphism alleles at the dopamine D1 and D2 receptor loci. No significant associations were found; thus, the hypothesis that a single mutant form of eit...
Topics
- Alleles
- Bipolar Disorder
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Phenotype
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine
- Receptors, Dopamine D1
- Receptors, Dopamine D2