Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism.

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Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism.

JAMA - 26 Dec 1990

Bolos A M, Dean M, Lucas-Derse S, Ramsburg M, Brown G L, Goldman D

Abstract excerpt

Using the dopamine D2 receptor clone lambda hD2G1, Blum et al recently found that the D2/Taq I allele (A1) was present in 69% of 35 deceased alcoholics but in only 20% of an equal number of controls. To assess this association further, we evaluated the D2/Taq I polymorphism and a single-strand conformation polymorphism detected by polymerase chain reaction and nondenaturing gel electrophoresis (PCR-SSCP) of the...

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Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism.

Abstract excerpt

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Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism.

Abstract excerpt

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