Article
Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism.
JAMA - 26 Dec 1990
Bolos A M, Dean M, Lucas-Derse S, Ramsburg M, Brown G L, Goldman D
Abstract excerpt
Using the dopamine D2 receptor clone lambda hD2G1, Blum et al recently found that the D2/Taq I allele (A1) was present in 69% of 35 deceased alcoholics but in only 20% of an equal number of controls. To assess this association further, we evaluated the D2/Taq I polymorphism and a single-strand co...
Topics
- Adult
- Aged
- Alcoholism
- Alleles
- Black People
- DNA Probes
- DNA, Single-Stranded
- Female
- Humans
- Male
- Middle Aged
- Pedigree
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine
- Receptors, Dopamine D2