Article
Identification of novel RFLPs in the vicinity of CpG islands in Xq28: application to the analysis of the pattern of X chromosome inactivation.
American journal of human genetics - 1 Jan 1992
Maestrini E, Rivella S, Tribioli C, Rocchi M, Camerino G, Santachiara-Benerecetti S, Parolini O, Notarangelo L D, Toniolo D
Abstract excerpt
Probes for CpG islands were cloned from the distal long arm of the human X chromosome; three of them were found to be polymorphic. A HindIII RFLP was identified by the probe 2-25 (DXS606), and it was mapped to the Xq27-Xq28 boundary. Probes 2-19 (DXS605) and 2-55 (DXS707), which identify EcoRI an...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Cricetinae
- DNA
- DNA Probes
- Dinucleoside Phosphates
- Female
- Genetic Linkage
- Humans
- Hybrid Cells
- Methylation
- Polymorphism, Restriction Fragment Length
- Restriction Mapping
- X Chromosome