Isolation of a GCC repeat showing expansion in FRAXF, a fragile site distal to FRAXA and FRAXE.

doi:10.1038/ng1194-229

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Isolation of a GCC repeat showing expansion in FRAXF, a fragile site distal to FRAXA and FRAXE.

Nature genetics - 1 Nov 1994

Parrish J E, Oostra B A, Verkerk A J, Richards C S, Reynolds J, Spikes A S, Shaffer L G, Nelson D L

Abstract excerpt

Three folate-sensitive fragile sites, termed FRAXA, FRAXE and FRAXF, have been identified on the distal end of chromosome Xq. The first two contain expanded, hypermethylated and unstable CGG (or GCC) repeats within CpG islands. We now report the isolation of similar sequences responsible for the...

Topics

Alleles
Animals
Base Sequence
Chromosome Fragile Sites
Chromosome Fragility
Cricetinae
Female
Fragile X Syndrome
Genetic Markers
Humans
Male
Methylation
Mice
Minisatellite Repeats
Molecular Sequence Data
Pedigree
X Chromosome

Source

Open in PubMed

Identifiers

PMID: 7874164
DOI: 10.1038/ng1194-229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7874164-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics