Article
Mapping the clock rhythm mutation to the period locus of Drosophila melanogaster by germline transformation.
Journal of neurogenetics - 1 Sept 1992
Dushay M S, Rosbash M, Hall J C
Abstract excerpt
The Clock (Clk) mutation shortens circadian rhythms of locomotor activity and eclosion from ca. 24 h to 22.5-23 h. Clk was previously mapped, by meiotic recombination, very close to the period(per) locus on the X chromosome. To determine whether Clk is a mutation within the per gene or if the former is separate from the latter, two overlapping genomic fragments were cloned from Clk flies to produce a...
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