Article
Phenotypic and genetic analysis of Clock, a new circadian rhythm mutant in Drosophila melanogaster.
Genetics - 1 Jul 1990
Dushay M S, Konopka R J, Orr D, Greenacre M L, Kyriacou C P, Rosbash M, Hall J C
Abstract excerpt
Clock is a semidominant X-linked mutation that results in shortening the period of Drosophila melanogaster's free-running locomotor activity rhythm from ca. 24.0 to ca. 22.5 hr. This mutation similarly shortened the phase response curve, determined by resetting activity rhythms with light pulses. Eclosion peaks for Clk cultures were separated by only 22.5 hr instead of the normal 24 hr. Clk was mapped close to,...
Topics
- Animals
- Chromosome Aberrations
- Chromosome Mapping
- Circadian Rhythm
- Drosophila melanogaster
- Motor Activity
- Mutation
- Phenotype
- Recombination, Genetic
- Temperature
- Time Factors