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Article

Phenotypic differences between Syrian hamster embryo cells cultured at pH 6.7 or 7.3.

In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Jan 2000

Isfort R J, Cody D B, Asquith T N, LeBoeuf R A

Abstract excerpt

We have investigated the molecular phenotypic differences between Syrian hamster embryo (SHE) cells cultured at pH 6.7 or 7.3. Multiple pH-sensitive phenotypic differences were noted including changes in cellular morphology, a unique charge differential in a major cellular protein, nine uniquely expressed proteins, two unique phosphoserine/threonine phosphoproteins, one unique phosphotyrosine phosphoprotein, and...

Topics

Animals
Cells, Cultured
Connexins
Cricetinae
Culture Media
Embryo, Mammalian
Hydrogen-Ion Concentration
Isoelectric Point
Membrane Proteins
Mesocricetus
Molecular Weight

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Phosphoproteins

Proteins

RNA, Messenger

Source

Identifiers

PMID: 1331022
DOI: 10.1007/BF02631039

Genes

SHE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1331022-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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