Phenotypically and karyotypically distinct Madin-Darby canine kidney cell clones respond differently to alkaline stress.

doi:10.1002/jcp.1041640121

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Article

Phenotypically and karyotypically distinct Madin-Darby canine kidney cell clones respond differently to alkaline stress.

Journal of cellular physiology - 1 Jul 1995

Wünsch S, Gekle M, Kersting U, Schuricht B, Oberleithner H

Abstract excerpt

We isolated two cell clones from the wild-type Madin-Darby canine kidney cell line (MDCK) that resembles renal collecting duct epithelium. Morphology and karyotypes of the two cell clones were evaluated. The MDCK-C7 cell clone morphologically resembles principal cells (polygonal cell shape, flat)...

Topics

Alkalies
Animals
Calcium
Cell Division
Cell Line
Clone Cells
Dogs
Hydrogen-Ion Concentration
Karyotyping
Kidney
Membrane Potentials
Oscillometry
Phenotype
Stress, Physiological

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