Article
Expanding the Spectrum of Renal Tumors in Children: Primary Renal Myoepithelial Carcinomas With a Novel EWSR1-KLF15 Fusion.
The American journal of surgical pathology - 1 Mar 2016
Cajaiba Mariana M, Jennings Lawrence J, Rohan Stephen M, Leuer Katrin M, Anagnost Miran R, Fahner James B, Fulton Barbara K, Geller James I, Perlman Elizabeth J
Abstract excerpt
We report the first 2 examples of primary renal myoepithelial carcinoma (MEC), both occurring in children. Both tumors had the unique morphologic features, immunophenotype, and EWSR1 gene rearrangements supporting the diagnosis. In keeping with the previous observations of an aggressive behavior in pediatric MEC, both cases presented with advanced local stage and distant metastases at the time of diagnosis. The...
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