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Article

The beta-subunit of the signal recognition particle receptor is a novel GTP-binding protein without intrinsic GTPase activity.

The Journal of biological chemistry - 25 Jul 2003

Legate Kyle R, Andrews David W

Abstract excerpt

The beta-subunit of the signal recognition particle receptor (SRbeta), a member of the Ras family of small molecular weight GTPases, is involved in the targeting of nascent polypeptide chains to the protein translocation machinery in the endoplasmic reticulum membrane. We purified SRbeta from an expressing strain of Escherichia coli and investigated the properties of the isolated GTPase. We find that, unlike...

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PMID: 12759365
DOI: 10.1074/jbc.M302158200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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