Molecular approaches to prevention and therapy of aerodigestive tract cancers.

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Article

Molecular approaches to prevention and therapy of aerodigestive tract cancers.

Journal of the National Cancer Institute. Monographs - 1 Jan 1992

Roth J A, Mukhopadhyay T, Tainsky M A, Fang K, Casson A G, Schneider P M

Abstract excerpt

We describe studies defining several molecular events in human non-small-cell lung cancer (NSCLC). These include increased growth factor and growth factor receptor expression and oncogene alterations. The epidermal growth factor receptor (EGFR) and erbB2 are expressed by NSCLC cells. Transforming...

Topics

Carcinoma, Non-Small-Cell Lung
DNA, Neoplasm
ErbB Receptors
Gene Expression Regulation, Neoplastic
Genes, p53
Genes, ras
Growth Substances
Humans
Lung Neoplasms
Mutation
Polymerase Chain Reaction
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1327031

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1327031-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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