Molecular surgery for cancer.

doi:10.1001/archsurg.1992.01420110040010

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Article

Molecular surgery for cancer.

Archives of surgery (Chicago, Ill. : 1960) - 1 Nov 1992

Roth J A

Abstract excerpt

Advances in the understanding of the process of carcinogenesis may allow prevention, diagnosis, and treatment of cancer to be approached at the molecular level. Studies in our laboratory show that growth factors (transforming growth factor alpha), dominant oncogenes (HER-2/erb B2 and K-ras), and tumor suppressor genes (p53) are functionally important in the maintenance of the malignant phenotype of human...

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PMID: 1444790
DOI: 10.1001/archsurg.1992.01420110040010

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