Article
Genetic polymorphism of the beta-2 adrenergic receptor in atopic and non-atopic subjects.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Oct 1993
Potter P C, Van Wyk L, Martin M, Lentes K U, Dowdle E B
Abstract excerpt
To investigate a possible genetic basis for reported differences in beta-2 receptor expression in atopic subjects, DNA from 42 atopic children (22 asthmatics and 22 with allergic rhinitis) and 30 non-atopic subjects was Southern blotted and Ban-1 restriction fragment polymorphisms (RFLPS) were studied using a 2.6 kb probe of the human beta-2 receptor gene. Two alleles 3.1 kb and 2.9 kb were identified....
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