Expression and transforming activity of a variant of the heparin-binding fibroblast growth factor receptor (flg) gene resulting from splicing of the alpha exon at an alternate 3'-acceptor site.

doi:10.1016/0006-291x(92)90498-a

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Article

Expression and transforming activity of a variant of the heparin-binding fibroblast growth factor receptor (flg) gene resulting from splicing of the alpha exon at an alternate 3'-acceptor site.

Biochemical and biophysical research communications - 16 Mar 1992

Yan G, Wang F, Fukabori Y, Sussman D, Hou J, McKeehan W L

Abstract excerpt

Splicing at an alternate 3'-acceptor site results in deletion of a CCCAG in the 5'-sequence of the exon coding for the NH2-terminal immunoglobulin-like disulfide loop of the heparin-binding fibroblast growth factor receptor (flg) alpha isoform. The result is an in-frame stop codon 138 base pairs...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Transformation, Neoplastic
Culture Media
DNA, Recombinant
Exons
Filaggrin Proteins
Gene Expression
Genetic Variation
Male
Molecular Sequence Data
Prostate
RNA Splicing
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 1312829
DOI: 10.1016/0006-291x(92)90498-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1312829-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Rats

Receptors, Cell Surface

Receptors, Fibroblast Growth Factor