Article
Receptor specificity of the fibroblast growth factor family.
The Journal of biological chemistry - 21 Jun 1996
Ornitz D M, Xu J, Colvin J S, McEwen D G, MacArthur C A, Coulier F, Gao G, Goldfarb M
Abstract excerpt
Fibroblast growth factors (FGFs) are essential molecules for mammalian development. The nine known FGF ligands and the four signaling FGF receptors (and their alternatively spliced variants) are expressed in specific spatial and temporal patterns. The activity of this signaling pathway is regulat...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Cell Line
- Fibroblast Growth Factors
- Genetic Variation
- Humans
- Kinetics
- Ligands
- Mice
- Molecular Sequence Data
- Protein-Tyrosine Kinases
- Receptor Protein-Tyrosine Kinases
- Receptor, Fibroblast Growth Factor, Type 1
- Receptor, Fibroblast Growth Factor, Type 2
- Receptor, Fibroblast Growth Factor, Type 3
- Receptor, Fibroblast Growth Factor, Type 4
- Receptors, Fibroblast Growth Factor