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Article

Transition of phenotypic dimorphism with regard to spontaneous sister chromatid exchange in Epstein-Barr virus-transformed Bloom's syndrome lymphoblastoid cell lines.

Japanese journal of cancer research : Gann - 1 Jul 1992

Tatsumi K, Kurihara T, Arita I, Tatsumi-Miyajima J

Abstract excerpt

We recently established four lymphoblastoid cell lines (LCLs) by infecting the peripheral blood of four Japanese patients suffering from Bloom's syndrome (BS) with Epstein-Barr virus (EBV). During the course of propagating these cell lines, two of them exhibited dimorphism regarding spontaneous sister chromatid exchange (SCE), i.e., a mixed population consisted of cells with extremely high SCE levels...

Topics

Adolescent
Bloom Syndrome
Cell Division
Cell Transformation, Viral
Cells, Cultured
Child
Female
Herpesvirus 4, Human
Humans
Lymphocytes
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Polymorphism, Genetic

Sister Chromatid Exchange

Source

Open in PubMed Open full text

Identifiers

PMID: 1325430
DOI: 10.1111/j.1349-7006.1992.tb01973.x
PMCID: PMC5918926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1325430-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Transition of phenotypic dimorphism with regard to spontaneous sister chromatid exchange in Epstein-Barr virus-transformed Bloom's syndrome lymphoblastoid cell lines.PMID 1325430Read ↗

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