Article
Herpesviruses encode an unusual protein-serine/threonine kinase which is nonessential for growth in cultured cells.
Journal of virology - 1 Sept 1992
de Wind N, Domen J, Berns A
Abstract excerpt
We have performed large-scale random oligonucleotide insertion mutagenesis on a 41-kbp genomic segment derived from the unique long (UL) region of the alphaherpesvirus pseudorabies virus (PRV). This procedure has resulted in the generation of a series of PRV strains, each carrying a single gene w...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Chromosome Mapping
- Gene Expression
- Herpesvirus 1, Suid
- Molecular Sequence Data
- Mutagenesis, Insertional
- Phenotype
- Phosphoserine
- Protein Biosynthesis
- Protein Kinases
- Protein Serine-Threonine Kinases
- Sequence Homology, Nucleic Acid
- Substrate Specificity