Molecular analysis of a pro-T cell clone transformed by Abelson-murine leukemia virus, displaying progressive gamma delta T cell receptor gene rearrangement and surface expression.

doi:10.1002/eji.1830220818

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Article

Molecular analysis of a pro-T cell clone transformed by Abelson-murine leukemia virus, displaying progressive gamma delta T cell receptor gene rearrangement and surface expression.

European journal of immunology - 1 Aug 1992

Heuze F, Pardoll D, Diez E, Ezine S, Jotereau F

Abstract excerpt

We present a molecular analysis of T cell differentiation in a set of clones derived from in vitro Abelson murine leukemia virus (A-MuLV) infection of fetal liver cells. The parental clone had partial rearrangement of the beta and gamma loci and spontaneously displayed progressive rearrangement of V gamma genes during in vitro culture. Further differentiation of these clones leading to delta gene rearrangement...

Topics

Abelson murine leukemia virus
Animals
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
CD8 Antigens
Cell Differentiation
Cell Transformation, Viral
Clone Cells
Gene Rearrangement, delta-Chain T-Cell Antigen Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor

Mice

Phenotype

Receptors, Antigen, T-Cell

Receptors, Antigen, T-Cell, gamma-delta

T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 1322302
DOI: 10.1002/eji.1830220818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1322302-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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