Insertional inactivation of a gene which controls expression of vancomycin resistance on plasmid pHKK100.

doi:10.1016/0378-1097(92)90533-t

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Article

Insertional inactivation of a gene which controls expression of vancomycin resistance on plasmid pHKK100.

FEMS microbiology letters - 1 Apr 1992

Handwerger S, Discotto L, Thanassi J, Pucci M J

Abstract excerpt

Expression of inducible high level vancomycin resistance (Vmr) in enterococci appears to require other plasmid-encoded genes in addition to the previously described structural genes vanA and vanH. Tn917 mutagenesis was used to identify such a region in the Vmr plasmid pHKK100. Insertional inactiv...

Topics

Amino Acid Sequence
Base Sequence
DNA Transposable Elements
Drug Resistance, Microbial
Enterococcus
Gene Expression
Molecular Sequence Data
Mutagenesis, Insertional
Phenotype
R Factors
Vancomycin

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