Article
Molecular basis of vancomycin dependence in VanA-type Staphylococcus aureus VRSA-9.
Journal of bacteriology - 1 Oct 2010
Meziane-Cherif Djalal, Saul Frederick A, Moubareck Carole, Weber Patrick, Haouz Ahmed, Courvalin Patrice, Périchon Bruno
Abstract excerpt
The vancomycin-resistant Staphylococcus aureus VRSA-9 clinical isolate was partially dependent on glycopeptide for growth. The responsible vanA operon had the same organization as that of Tn1546 and was located on a plasmid. The chromosomal D-Ala:D-Ala ligase (ddl) gene had two point mutations th...
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