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Article

Moderate-level resistance to glycopeptide LY333328 mediated by genes of the vanA and vanB clusters in enterococci.

Antimicrobial agents and chemotherapy - 1 Aug 1999

Arthur M, Depardieu F, Reynolds P, Courvalin P

Abstract excerpt

Three of five natural plasmids carrying a wild-type vanA gene cluster did not confer LY333328 glycopeptide resistance on Enterococcus faecalis JH2-2 (MIC = 2 microg/ml). The two remaining plasmids conferred resistance to the drug (MIC, 8 microg/ml). The vanB gene cluster did not confer resistance to LY333328, since this antibiotic was not an inducer. Mutations in the vanS(B) sensor gene that allowed induction by...

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Identifiers

PMID: 10428906
DOI: 10.1128/AAC.43.8.1875
PMCID: PMC89384

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Moderate-level resistance to glycopeptide LY333328 mediated by genes of the vanA and vanB clusters in enterococci.PMID 10428906Read ↗

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Novel mechanism of glycopeptide resistance in the A40926 producer Nonomuraea sp. ATCC 39727.Semantic proximity Read ↗

VanD-Type Vancomycin-Resistant Enterococcus faecium and Enterococcus faecalisSemantic proximity Read ↗

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