Article
Specificity of induction of glycopeptide resistance genes in Enterococcus faecalis.
Antimicrobial agents and chemotherapy - 1 Oct 1996
Baptista M, Depardieu F, Courvalin P, Arthur M
Abstract excerpt
Regulation of VanA- and VanB-type glycopeptide resistance in enterococci is mediated by related two-component regulatory systems (VanR-VanS and VanRB-VanSB). The transglycosylase inhibitors vancomycin, teicoplanin, and moenomycin induced synthesis of the VanX D,D-dipeptidase in a VanA-type Enterococcus faecalis harboring transposon Tn1546. Inhibitors of reactions immediately preceding (ramoplanin) or following...
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