Article
Discovery of a genetic polymorphism of human plasma protein C inhibitor (PCI): genetic survey utilizing isoelectric focusing followed by immunoblotting, immunological and biochemical characterization.
Human genetics - 1 May 1992
Yasuda T, Nadano D, Iida R, Tanaka Y, Nakanaga M, Kishi K
Abstract excerpt
The objectives of this study were to determine the genetic basis of the electrophoretic differences of human plasma protein C inhibitors (PCI) from 977 individuals. Three discrete antibodies were produced against the PCI purified from human plasma and peptides that corresponded to the N-terminal...
Topics
- Alleles
- Amino Acid Sequence
- Asian People
- Female
- Gene Frequency
- Humans
- Immunoblotting
- Isoelectric Focusing
- Male
- Molecular Sequence Data
- Pedigree
- Phenotype
- Plasminogen Inactivators
- Polymorphism, Genetic
- Protein C
- Protein C Inhibitor