Article
Genetic polymorphism of inter-alpha-trypsin-inhibitor (ITI): formal genetic and linkage analyses.
Human genetics - 1 May 1991
Luckenbach C, Kömpf J, Ritter H
Abstract excerpt
The polymorphism of inter-alpha-trypsin-inhibitor, ITI, was demonstrated by isoelectric focusing in agarose gels (pH 5-8) followed by protein blotting and immunoassay. Segregation in 239 families with 677 children is consistent with the formal hypothesis that there are two common codominant alleles, ITI*1, ITI*2, and one rare codominant allele, ITI*3, at an autosomal locus ITI. Allele frequencies were calculated...
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