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Article

Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.

1 Jun 1992

Abstract excerpt

Two chimeric genes, PML-RAR alpha and RAR alpha-PML, are formed as a consequence of the acute promyelocytic leukemia (APL)-specific reciprocal translocation of chromosomes 15 and 17 [t(15;17)]. PML-RAR alpha is expressed as a fusion protein. We investigated the organization and expression pattern of the RAR alpha-PML gene in a series of APL patients representative of the molecular heterogeneity of the t(15;17)...

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Identifiers

PMID: 1317574
DOI: 10.1073/pnas.89.11.4840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.PMID 1317574Read ↗

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