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Article

Cytomegalovirus determinant of replication in salivary glands.

Journal of virology - 1 Jun 1992

Manning W C, Stoddart C A, Lagenaur L A, Abenes G B, Mocarski E S

Abstract excerpt

Murine cytomegalovirus carrying a deletion mutation disrupting the expression of a gene dispensable for growth in cultured cells was found to disseminate poorly in the mouse. The mutation resulted in a dramatic decrease in the expression of a 1.5-kb major and a 1.8-kb minor beta transcript from a region adjacent to the ie2 gene in the viral genome. Nucleotide sequence determination indicated that 323 bp,...

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Identifiers

PMID: 1316482
DOI: 10.1128/JVI.66.6.3794-3802.1992
PMCID: PMC241165

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