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Article

Cytomegalovirus determinant of replication in salivary glands.

Journal of virology - 1 Jun 1992

Manning W C, Stoddart C A, Lagenaur L A, Abenes G B, Mocarski E S

Abstract excerpt

Murine cytomegalovirus carrying a deletion mutation disrupting the expression of a gene dispensable for growth in cultured cells was found to disseminate poorly in the mouse. The mutation resulted in a dramatic decrease in the expression of a 1.5-kb major and a 1.8-kb minor beta transcript from a region adjacent to the ie2 gene in the viral genome. Nucleotide sequence determination indicated that 323 bp,...

Topics

3T3 Cells
Animals
Base Sequence
Cytomegalovirus
DNA, Recombinant
Host-Parasite Interactions
Male
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Mutation
Organ Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Regulatory Sequences, Nucleic Acid

Salivary Glands

Transcription, Genetic

Viremia

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 1316482
DOI: 10.1128/JVI.66.6.3794-3802.1992
PMCID: PMC241165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1316482-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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