Article
Control of murine cytomegalovirus replication in salivary glands during acute infection is independent of the Fas ligand/Fas system.
The new microbiologica - 1 Jul 2001
Riera L, Gariglio M, Pagano M, Gaiola O, Simon M M, Landolfo S
Abstract excerpt
The course of mouse cytomegalovirus (MCMV) infection was compared between mutant C57BL/6 (B6) mice deficient in either perforin (perf-/-), or perforin, granzyme A and B (perfxgzmAxB-/-), and B6 gld mice lacking functionally active Fas ligand to elucidate the contribution of the two main cytolytic pathways in the early control of MCMV infection. At 15 and 30 days post infection (p.i.) virus titers were elevated in...
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