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Article

Mutations within the env gene of Mason-Pfizer monkey virus: effects on protein transport and SU-TM association.

Journal of virology - 1 Jun 1992

Brody B A, Hunter E

Abstract excerpt

By deletion mutagenesis analyses, we have examined the contribution of the immunosuppressive peptide (ISP) region within the transmembrane (TM) protein of Mason-Pfizer monkey virus to viral maturation and infectivity. Deletion of the entire region (mutant D105) results in the production of an Env precursor that is transport defective and therefore unable to be processed to mature glycoproteins. This mutation...

Topics

Amino Acid Sequence
Animals
Biological Transport, Active
DNA Mutational Analysis
Genes, env
Genetic Vectors
Humans
Mason-Pfizer monkey virus
Molecular Sequence Data
Phenotype
Protein Processing, Post-Translational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Virus

Simian virus 40

Viral Envelope Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1316462
DOI: 10.1128/JVI.66.6.3466-3475.1992
PMCID: PMC241127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1316462-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Mutations within the env gene of Mason-Pfizer monkey virus: effects on protein transport and SU-TM association.PMID 1316462Read ↗

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