Article
Evidence that polymorphism of the angiotensin I converting enzyme gene may be related to idiopathic dilated cardiomyopathy in the Chinese population.
Biochemistry and molecular biology international - 1 May 1995
Harn H J, Chang C Y, Ho L I, Liu C A, Jeng J R, Lin F G, Jent-Wei
Abstract excerpt
Angiotensin I-converting enzyme (ACE) is responsible for the production of angiotension II and the breakdown of kinins, leading to increased blood pressure (BP), induction of vascular smooth muscle cell proliferation, and the stimulation of myocardial-cell hypertrophy. A 287 bp insertion/deletion...
Topics
- Adult
- Alleles
- Base Sequence
- Cardiomyopathy, Dilated
- China
- DNA Transposable Elements
- Gene Deletion
- Genotype
- Humans
- Introns
- Molecular Sequence Data
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic