Article
Association of variants in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension in Japanese.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 1997
Sato N, Katsuya T, Rakugi H, Takami S, Nakata Y, Miki T, Higaki J, Ogihara T
Abstract excerpt
We examined the association between variants in the core promoter element 1 (AGCE1) of the human angiotensinogen gene (AGT), which acts as a critical regulator of AGT transcription, and the risk for hypertension. One hundred and eighty patients with documented essential hypertension and a family...
Topics
- Aged
- Alleles
- Angiotensinogen
- Asian People
- Base Sequence
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Linkage
- Genetic Variation
- Genotype
- Humans
- Hypertension
- Japan
- Male
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction