Article
Association of variants in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension in Japanese.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 1997
Sato N, Katsuya T, Rakugi H, Takami S, Nakata Y, Miki T, Higaki J, Ogihara T
Abstract excerpt
We examined the association between variants in the core promoter element 1 (AGCE1) of the human angiotensinogen gene (AGT), which acts as a critical regulator of AGT transcription, and the risk for hypertension. One hundred and eighty patients with documented essential hypertension and a family history of hypertension and 194 control subjects without hypertension were selected and frequency matched by age and...
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