Twelve-nucleotide repeat polymorphism of D4 dopamine receptor gene in Chinese familial schizophrenic patients.

doi:10.1016/s0006-3223(97)00207-2

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Article

Twelve-nucleotide repeat polymorphism of D4 dopamine receptor gene in Chinese familial schizophrenic patients.

Biological psychiatry - 15 Mar 1998

Hong C J, Chiu H J, Chang Y S, Sim C B

Abstract excerpt

BACKGROUND: Disturbances in dopaminergic transmission have been implicated in the etiology of schizophrenia. Catalano et al reported an association between delusional disorder and the number of a 12-nucleotide (bp) repeat sequence in the first exon of dopamine D4 receptor gene (DRD4), which indic...

Topics

Adult
Alleles
China
DNA
Female
Genotype
Humans
Male
Polymorphism, Genetic
Receptors, Dopamine D2
Receptors, Dopamine D4
Repetitive Sequences, Nucleic Acid
Schizophrenia

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