Article
Twelve-nucleotide repeat polymorphism of D4 dopamine receptor gene in Chinese familial schizophrenic patients.
Biological psychiatry - 15 Mar 1998
Hong C J, Chiu H J, Chang Y S, Sim C B
Abstract excerpt
BACKGROUND: Disturbances in dopaminergic transmission have been implicated in the etiology of schizophrenia. Catalano et al reported an association between delusional disorder and the number of a 12-nucleotide (bp) repeat sequence in the first exon of dopamine D4 receptor gene (DRD4), which indicated a possible role of this polymorphism in the pathogenesis of psychotic disorders. METHODS: DNA of 42 Chinese...
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