Article
Naturally occurring point mutation in the C terminus of the polymerase gene prevents duck hepatitis B virus RNA packaging.
Journal of virology - 1 Feb 1992
Chen Y, Robinson W S, Marion P L
Abstract excerpt
A duck hepatitis B virus (DHBV) genome cloned from a domestic duck from the People's Republic of China has been sequenced and exhibits no variation in sequences known to be important in viral replication or generation of gene products. Intrahepatic transfection of a dimer of this viral genome int...
Topics
- Amino Acid Sequence
- Animals
- Blotting, Southern
- Capsid
- Cell Line
- Chickens
- Cloning, Molecular
- DNA, Viral
- DNA-Directed RNA Polymerases
- Ducks
- Genes, Viral
- Genome, Viral
- Hepatitis B Virus, Duck
- Mutagenesis, Site-Directed
- Mutation
- RNA, Viral
- Ribonuclease H
- Transfection