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Article

Clinical implications of variable antiarrhythmic drug metabolism.

Pharmacogenetics - 1 Feb 1992

Buchert E, Woosley R L

Abstract excerpt

Due to their narrow therapeutic indices, antiarrhythmic drugs have a great potential for adverse outcome. This is amplified by extreme inter-individual variability in their disposition and their pharmacological actions. Genetically determined inter-individual differences in metabolism account for a great deal of this variability. However, because of active metabolites, chirally-specific actions and...

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Identifiers

PMID: 1302039
DOI: 10.1097/00008571-199202000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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