Cellular localization of Nef expressed in persistently HIV-1-infected low-producer astrocytes.

doi:10.1097/00002030-199212000-00002

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Article

Cellular localization of Nef expressed in persistently HIV-1-infected low-producer astrocytes.

AIDS (London, England) - 1 Dec 1992

Kohleisen B, Neumann M, Herrmann R, Brack-Werner R, Krohn K J, Ovod V, Ranki A, Erfle V

Abstract excerpt

OBJECTIVES: The characterization and localization of HIV-1 Nef highly expressed in permanently infected astrocytes (TH4-7-5) as a model for latent infection of human brain cells. DESIGN: Immunochemical methods are an appropriate tool to investigate expression and localization of cellular proteins. METHODS: Nef expression was analysed by Western blot and immunoperoxidase staining using a panel of monoclonal and...

Topics

Amino Acid Sequence
Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral
Astrocytes
Cell Compartmentation
Gene Products, nef
Genetic Variation
HIV-1
Humans
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Myristic Acid

Myristic Acids

Nuclear Envelope

Peptide Fragments

Protein Processing, Post-Translational

Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 1301062
DOI: 10.1097/00002030-199212000-00002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1301062-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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