Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chondrodysplasia of gene knockout mice for aggrecan and link protein.

Glycoconjugate journal - 1 Jan 2000

Watanabe Hideto, Yamada Yoshihiko

Abstract excerpt

The proteoglycan aggregate of the cartilage is composed of aggrecan, link protein, and hyaluronan and forms a unique gel-like moiety that provides resistance to compression in joints and a foundational cartilage structure critical for growth plate formation. Aggrecan, a large chondroitin sulfate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aggrecans
Share to Extracellular Matrix Proteins
Share to Lectins, C-Type

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Molecular Structure

Share to Osteochondrodysplasias

Share to Proteins

Share to Proteoglycans

Source

Identifiers

PMID: 12975605
DOI: 10.1023/A:1025344332099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12975605-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chondrodysplasia of gene knockout mice for aggrecan and link protein.PMID 12975605Read ↗

Dwarfism and age-associated spinal degeneration of heterozygote <i>cmd</i> mice defective in aggrecanSemantic proximity Read ↗

Molecular genetics of chondrodysplasias, including clues to development, structure, and function.Semantic proximity Read ↗

Genetic rescue of chondrodysplasia and the perinatal lethal effect of cartilage link protein deficiency.Semantic proximity Read ↗

Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryosSemantic proximity Read ↗

A missense mutation (C667F) in β-dystroglycan results in reduced dystroglycan protein levels leading to myopathy and destabilization of the blood-brain and blood-retinal barrier protein networkSemantic proximity Read ↗

Human genetic disorders and knockout mice deficient in glycosaminoglycan.Semantic proximity Read ↗

Interruption of glycosphingolipid synthesis enhances osteoarthritis development in miceSemantic proximity Read ↗

The missense mutation C667F in murine β-dystroglycan causes embryonic lethality, myopathy and blood-brain barrier destabilization.Semantic proximity Read ↗

Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210.Semantic proximity Read ↗

Biglycan knockout mice: new models for musculoskeletal diseases.Semantic proximity Read ↗

Investigating the functions of LARGE: lessons from mutant mice.Semantic proximity Read ↗

Heparan sulfate: lessons from knockout mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.