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Article

Puralpha is essential for postnatal brain development and developmentally coupled cellular proliferation as revealed by genetic inactivation in the mouse.

Molecular and cellular biology - 1 Oct 2003

Khalili Kamel, Del Valle Luis, Muralidharan Vandhana, Gault William J, Darbinian Nune, Otte Jessica, Meier Ellen, Johnson Edward M, Daniel Dianne C, Kinoshita Yayoi, Amini Shohreh, Gordon Jennifer

Abstract excerpt

The single-stranded DNA- and RNA-binding protein, Puralpha, has been implicated in many biological processes, including control of transcription of multiple genes, initiation of DNA replication, and RNA transport and translation. Deletions of the PURA gene are frequent in acute myeloid leukemia....

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Identifiers

PMID: 12972605
DOI: 10.1128/MCB.23.19.6857-6875.2003
PMCID: PMC193944

Genes

MCM7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12972605-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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