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Article

Role of metalloprotease disintegrin ADAM12 in determination of quiescent reserve cells during myogenic differentiation in vitro.

Molecular and cellular biology - 1 Oct 2003

Cao Yi, Zhao Zhefeng, Gruszczynska-Biegala Joanna, Zolkiewska Anna

Abstract excerpt

Skeletal myoblasts grown in vitro and induced to differentiate either form differentiated multinucleated myotubes or give rise to quiescent, undifferentiated "reserve cells" that share several characteristics with muscle satellite cells. The mechanism of determination of reserve cells is poorly understood. We find that the expression level of the metalloprotease disintegrin ADAM12 is much higher in proliferating...

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Identifiers

PMID: 12972593
DOI: 10.1128/MCB.23.19.6725-6738.2003
PMCID: PMC193919

Genes

ADAM12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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