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Article

Microrna-221 and microrna-222 modulate differentiation and maturation of skeletal muscle cells.

PloS one - 27 Oct 2009

Cardinali Beatrice, Castellani Loriana, Fasanaro Pasquale, Basso Annalisa, Alemà Stefano, Martelli Fabio, Falcone Germana

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are a class of small non-coding RNAs that have recently emerged as important regulators of gene expression. They negatively regulate gene expression post-transcriptionally by translational repression and target mRNA degradation. miRNAs have been shown to play crucial roles in muscle development and in regulation of muscle cell proliferation and differentiation. METHODOLOGY/PRINCIPAL...

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Identifiers

PMID: 19859555
DOI: 10.1371/journal.pone.0007607
PMCID: PMC2762614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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