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Article

Transcriptional activity of testis-determining factor SRY is modulated by the Wilms' tumor 1 gene product, WT1.

Oncogene - 11 Sept 2003

Matsuzawa-Watanabe Yumiko, Inoue Jun-Ichiro, Semba Kentaro

Abstract excerpt

The Wilms' tumor 1 (WT1) and sex-determining region of the Y chromosome (SRY) genes are essential for development of the mammalian gonads and mutations in these genes are associated with gonadal dysgenesis in humans. The SRY gene encodes a transcription factor with one high-mobility group (HMG) b...

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Source

Identifiers

PMID: 12970737
DOI: 10.1038/sj.onc.1206717

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12970737-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Transcriptional activity of testis-determining factor SRY is modulated by the Wilms' tumor 1 gene product, WT1.PMID 12970737Read ↗

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