Article
[Association of single nucleotide polymorphism in matrix metalloproteinases promoter with susceptibility to ovarian cancer].
Zhonghua fu chan ke za zhi - 1 Jul 2005
Li Yan, Wang Ying, Kang Shan, Zhang Jian-hui, Guo Wei, Wang Na, Jin Xia, Fang Shu-mei
Abstract excerpt
OBJECTIVE: To investigate the association of single nucleotide polymorphism in matrix metalloproteinase (MMP)-1 and MMP-3 promoter with susceptibility to ovarian cancer. METHODS: The genotype of MMP-1 and MMP-3 gene promoter region was determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 122 ovarian cancer patients (ovarian cancer group) and 151 unrelated healthy women...
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