Article
Mutational analysis of Noxa gene in human cancers.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jun 2003
Lee Sug Hyung, Soung Young Hwa, Lee Jong Woo, Kim Hong Sug, Lee Jong Heun, Kim Hong Sug, Lee Jong Heun, Park Jik Young, Cho Yong Gu, Kim Chang Jae, Kim Su Young, Park Won Sang, Kim Sang Ho, Lee Jung Young, Yoo Nam Jin
Abstract excerpt
There has been mounting evidence that dysregulation of apoptosis is involved in the mechanisms of cancer development and somatic mutations of apoptosis-related genes have been reported in human cancers. Noxa, a Bcl-2 homology 3 (BH3)-only member of the Bcl-2 family, is known to interact with anti...
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