Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Noxa in colorectal cancer: a study on DNA, mRNA and protein expression.

Oncogene - 24 Jul 2003

Jansson Agneta K, Emterling Anna M, Arbman Gunnar, Sun Xiao-Feng

Abstract excerpt

Noxa is a BH3-only member of the Bcl-2 family, upregulated by p53 as a response to DNA damage. Mutations in the BH3-only region of other BH3-only members lead to an inactive protein. We have investigated the mRNA expression of Noxa with real-time PCR in 94 unselected colorectal adenocarcinomas an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Colorectal Neoplasms
Share to Polymorphism, Single-Stranded Conformational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Structure, Tertiary

Share to Proto-Oncogene Proteins c-bcl-2

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA, Messenger

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 12879012
DOI: 10.1038/sj.onc.1206655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12879012-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Noxa in colorectal cancer: a study on DNA, mRNA and protein expression.PMID 12879012Read ↗

Mutational analysis of Noxa gene in human cancers.Semantic proximity Read ↗

MiR-200c Regulates Noxa Expression and Sensitivity to Proteasomal InhibitorsSemantic proximity Read ↗

Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras.Semantic proximity Read ↗

PNAS-4 expression and its relationship to p53 in colorectal cancer.Semantic proximity Read ↗

Analysis of mRNA transcripts from the NAD(P)H oxidase 1 (Nox1) gene. Evidence against production of the NADPH oxidase homolog-1 short (NOH-1S) transcript variant.Semantic proximity Read ↗

Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation.Semantic proximity Read ↗

Protein expression of NF-kappaB in human colorectal adenocarcinoma.Semantic proximity Read ↗

In vitro binding properties of tumor suppressor p53 with PUMA and NOXA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.