Article
Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae.
DNA repair - 18 Sept 2003
Mallory Julia C, Bashkirov Vladimir I, Trujillo Kelly M, Solinger Jachen A, Dominska Margaret, Sung Patrick, Heyer Wolf Dietrich, Petes Thomas D
Abstract excerpt
In eukaryotes, mutations in a number of genes that affect DNA damage checkpoints or DNA replication also affect telomere length [Curr. Opin. Cell Biol. 13 (2001) 281]. Saccharomyces cerevisae strains with mutations in the TEL1 gene (encoding an ATM-like protein kinase) have very short telomeres,...
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