Article
Association between dopamine receptor D1 gene DdeI polymorphism and sensation seeking in alcohol-dependent men.
Alcoholism, clinical and experimental research - 1 Aug 2003
Limosin Frédéric, Loze Jean-Yves, Rouillon Frédéric, Adès Jean, Gorwood Philip
Abstract excerpt
BACKGROUND: Among genetic and biopsychological factors involved in alcohol-dependence vulnerability, dopamine receptor subtypes genes and temperament's dimensions, such as sensation seeking, have been particularly incriminated. Moreover, it is suggested that higher levels of sensation seeking could be associated with a modification of sensitivity to dopamine in postsynaptic receptors. METHODS: We investigated...
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