Alcohol consumption is associated with an interaction between DRD2 exon 8 A/A genotype and self-directedness in males.

doi:10.1159/000109974

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Article

Alcohol consumption is associated with an interaction between DRD2 exon 8 A/A genotype and self-directedness in males.

Neuropsychobiology - 1 Jan 2007

Lucht Michael, Barnow Sven, Schroeder Winnie, Grabe Hans Joergen, Rosskopf Dieter, Brummer Christian, John Ulrich, Freyberger Harald J, Herrmann Falko H

Abstract excerpt

BACKGROUND: Both reduced postsynaptic dopamine D(2) receptor function and the character variable self-directedness (SDD) are related to the level of alcohol consumption. We examined for interactions between DRD2 exon 8(rs6276), a polymorphism which has been associated with various alcohol-related phenotypes, SDD and alcohol consumption. METHODS: A total of 144 male and 186 female probands with alcohol dependence...

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PMID: 17943029
DOI: 10.1159/000109974

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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