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Article

Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines.

Journal of hematotherapy & stem cell research - 1 Aug 2003

Kaplan Mark H, Chang Hua-Chen, Cooper Scott, Lee Younghee, Broxmeyer Hal E

Abstract excerpt

Hematopoietic progenitor cell (HPC) homeostasis is critical in maintaining innate immunity and healing processes. Recently, we demonstrated that Th1 cells regulate HPC homeostasis, partly based on altered homeostasis in Stat4- and Stat6-deficient mice. To explore changes in HPC responsiveness in altered T helper cell environments, we directly examined growth factor-stimulated colony formation and...

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Source

Identifiers

PMID: 12965077
DOI: 10.1089/152581603322286033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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