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Article

Phenotypic alterations in breast cancer cells overexpressing the nuclear receptor co-activator AIB1.

BMC cancer - 10 Sept 2003

Anzick Sarah L, Azorsa David O, Simons S Stoney, Meltzer Paul S

Abstract excerpt

BACKGROUND: Estrogen signaling plays a critical role in a number of normal physiological processes and has important implications in the treatment of breast cancer. The p160 nuclear receptor coactivator, AIB1 (amplified in breast cancer 1), is frequently amplified and overexpressed in human breast cancer and has been shown to enhance estrogen-dependent transactivation. METHODS: To better understand the molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12964942
DOI: 10.1186/1471-2407-3-22
PMCID: PMC201023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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